Online Health Expert's Global, Online and Free "Move Movement" Updated to Include the Role of "Sirtuins" That Have Been Shown to Play a Pivotal Role in Regulation of Lifespan.

An excerpt from Online Health Expert Dr. Harish Malik's Global, Online and Free "Move Movement" showing the Role of "Sirtuins" and their connection with Calorie Restriction (CR) and Physical Activity (PA) that play a Pivotal Role in Anti-aging and have been shown to Promote Longevity.


Cutting calories/ Calorie Restriction (CR) and Physical Activity (PA) (CR has been shown to promote longevity) - promotes mobility (as the body retains the drive to do things after a lighter meal as opposed to a heavy meal) , moves lymph (which is 3 times the amount of total blood in our body and is dependent on body movement to keep it flowing - lymph is the policeman, garbage man and the immigration system of our body) better by negating the effects of gravity (Taller people are at greater risk of developing Cancer), and helps prevent/fight infections and cancer.

The Biochemical basis of Calorie Restriction (CR) and Physical Activity (PA) leading to its Anti-Aging effects has been recently linked to Sirtuins which have been shown to play a pivotal role in regulation of Lifespan. Dr. Franklin H. Epstein's (June 9, 2011) Lecture "Sirtuins, Aging, and Medicine" accessible at The New England Journal of Medicine details the role and pathways of Sirtuins in the pathways of aging. In an article "Role of Sirtuins, calorie restriction and physical activity in aging" [Frontiers in Bioscience (Elite Edn.) Jan 01, 2012], a team of Italian researchers point out the clear-cut relationship between Sirt-1 and Calorie Restriction (CR) and in rats they showed that the levels of SIRT1 activity were raised in aged rats who performed moderately prolonged Physical Activity (PA). They found that in mammals, CR causes physiological and behavioral changes that lead to decreases in reactive oxygen species, thereby reducing oxidative stress and damage and thus leads to the hypothesis that CR by reducing oxidative stress extends lifespan by counteraction of aging.


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Online Health Expert Dr. Harish Malik's Global, Online and Free "Move Movement"


Thank you for learning about the Roles of PA, CR and Sirtuins in promoting meaningful Longevity.


Sincerely,


Dr. Harish Malik